Extracellular vesicles captured by sustainable wood cellulose-based nanofiber may identify and improve cancer treatment

By Nagoya University
Phys.Org
November 8, 2023
Category: Health & Safety
Region: International

A research team in Japan, led by Nagoya University’s Akira Yokoi, has developed an innovative technique using cellulose nanofiber (CNF) sheets derived from wood cellulose to capture extracellular vesicles (EVs) from fluid samples and even organs during surgery. EVs are small structures from cancerous cells that play a crucial role in cell-to-cell communication. Extracting and analyzing EVs using this new technology has the potential to revolutionize early cancer diagnosis and open the door to personalized medicine. The researchers have published their findings in Nature Communications. …Detecting the cancer early using EVs and analyzing them provides vital information on disease status and its progression. This should assist physicians in monitoring and adjusting personalized cancer treatment plans. However, researchers have been limited in previous attempts to use EVs due to the lack of an effective isolation strategy.

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